Husband and wife from Indiana arrested for exposing 10-month-old to illegal drug, leading to hospitalization. Neglect charges ...

Head-on crash on State Road 135 in Indiana leaves 65-year-old man dead. Investigation pending. Second driver received minor ...

Philip Rivers returned to the Colts after nearly five years away from the NFL, putting up a fight against the Seahawks. Colts ...

At least 11 people killed in a terror attack on Jewish community celebrating Hanukkah at Sydney's Bondi Beach. Investigations ...

FORT WAYNE, Ind. (WISH) — A 75-year-old Fort Wayne man was arrested and preliminarily charged with attempted murder after a ...

Learn about frostbite, its symptoms, and how to prevent it. Central Indiana emergency rooms report cold-related injuries.

After a record cold Sunday and several inches of snow Saturday, we’re in for a big warmup this week that brings back rain ...

Police arrived at the home and a 20-year-old man ran. Police officers found him armed with a knife in an alley near 22nd ...

Indiana sues operators of 50 pornographic websites, accusing them of violating age-verification law and exposing children to ...

Colts head coach Shane Steichen confirms Philip Rivers will start against the 49ers. Steichen praises Rivers' performance in ...

Kidney cancer survival rates are improving with new immunotherapy drug combinations, giving patients more years to live than ...