Focusing on an enzyme in yeast, they demonstrated how contrasts in atomic scale motions impact their function. The method ...

Chemical structure for thiamine pyrophosphate and protein structure of transketolase. Thiamine pyrophosphate cofactor in yellow and xylulose 5-phosphate substrate in black. Credit: Thomas ...

A new artificial intelligence tool can predict the functions of enzymes based on their amino acid sequences, even when the enzymes are unstudied or poorly understood. The researchers said the AI tool, ...

A new artificial intelligence-powered tool can help researchers determine how well an enzyme fits with a desired target, ...

Researchers from Tokyo Metropolitan University have developed a new structure determination method using Nuclear Magnetic ...

IVD is a key enzyme in leucine catabolism, catalyzing the conversion of isovaleryl-CoA to 3-methylcrotonyl-CoA. Defects in IVD function lead to toxic accumulation of metabolites such as isovaleric ...

Another protein central to this process is NuMA, which is essential for spindle pole organisation. Normally, NuMA gathers at ...

Usually enzyme complexes make multistep processes easier by catalyzing sequential reactions in which the product of one enzyme becomes the substrate for the next. In a new finding, researchers report ...

Dr. Ahmed Lawan, an assistant professor in the College of Science at The University of Alabama in Huntsville (UAH), a part of ...

In this corner: the state-of-the-art enzyme function prediction tool … the Bioinformatic Brawler … the Basic Local Alignment Search Tool for proteins … BLASTp! And in this corner: the contender … the ...