High-throughput parallel transfection techniques are a prerequisite to perform large-scale experiments, such as genome-wide RNAi screens, in mammalian tissue culture cells 1,2,3,4. In such studies, ...

The rise of high-throughput sequencing methodologies has greatly affected the ways in which biological problems are addressed. In particular, in microorganisms, the availability of complete genome ...

Palo Alto, Calif.-based BD Biosciences Clontech has expanded its family of reverse-format patient and cell-line cDNA arrays. Most arrays spot single genes, and scientists probe them with labeled mRNA ...

The quest to cure cancer requires an ever-expanding tool kit to identify and validate biomarkers for better detection, diagnosis, prognosis, and treatment of cancer. The vast number of discoveries ...