Blinatumomab is a bispecific CD19-directed CD3 T-cell engager. The Food and Drug Administration (FDA) has approved Blincyto ® (blinatumomab) for the treatment of adult and pediatric patients 1 month ...

In the Phase III GIMEMA ALL2820 trial, presented at ASH, 94 percent of patients who received the chemo-free regimen had a ...

Randomized Prospective Biomarker Trial of ERCC1 for Comparing Platinum and Nonplatinum Therapy in Advanced Non–Small-Cell Lung Cancer: ERCC1 Trial (ET) The frequency of Ph-like ALL was assessed by ...

Addition of imatinib to intensive chemotherapy improved survival for children and young adults with Philadelphia chromosome–positive acute lymphoblastic leukemia. Compared with imatinib, dasatinib has ...

However, neither the Philadelphia chromosome nor BCR-ABL is pathognomonic of CML, as they are present in other human hematologic malignancies. p210 BCR-ABL is found in 95% of patients with CML, but is ...

Peter Nowell, an acclaimed cancer researcher, died of Alzheimer’s disease complications on December 26 at age 88. Nowell is best known for co-discovering the Philadelphia chromosome while at the ...

Please provide your email address to receive an email when new articles are posted on . The FDA granted accelerated approval to ponatinib with chemotherapy for the treatment of adults with newly ...

ROCKVILLE, Md. and SUZHOU, China, March 05, 2025 (GLOBE NEWSWIRE) -- Ascentage Pharma (NASDAQ: AAPG; HKEX: 6855), a global biopharmaceutical company engaged in discovering, developing, and ...

The chemotherapy-free regimen achieved higher remission, better survival, and stronger molecular responses than the ...

It honors the 50th anniversary of the discovery that genes could cause cancer. Cancer researchers from around the country are in Philadelphia today feting the 50th anniversary of the discovery of the ...