However, many women with BRCA mutations perceive MHT as unsafe, due to concerns about their already elevated breast cancer ...

New research published in Nature Communications has linked a normal cellular process to an accumulation of DNA mutations in ...

Using menopausal hormone therapy (MHT) was not associated with an increased risk of breast cancer in women with inherited ...

The order of cancer-driving mutations—genetic changes—plays an important role in whether tumors in the intestine can develop, ...

A closeup look at colibactin’s structure reveals chemical motifs that guide its mutation-wreaking “warheads” to specific stretches of DNA.

Scientists discovered that certain cancer cells use a low-level activation of a DNA-dismantling enzyme—normally seen in cell ...

How bladder cancer originates and progresses has been illuminated as never before. Researchers found that antiviral enzymes that mutate the DNA of normal and cancer cells are key promoters of early ...

Indian scientists found a unique CASP8 driver mutation causing aggressive oral cancer in women in southern India. AI analysis showed two patient groups, underscoring need for better screening and ...

Hereditary breast cancer results from inherited mutations, primarily in BRCA1 and BRCA2, increasing lifetime cancer risk. Additional genes like TP53, PTEN, PALB2, CHEK2, and ATM also contribute to ...

A genetic fault long believed to drive the development of esophageal cancer may in fact play a protective role early in the disease, according to new research published in Nature Cancer. This ...