Reciprocal translocations are one of the most common structural chromosome abnormalities in our species and are present in one in 500 unselected newborns studied with a moderate level of banding. 1 ...

Apparently balanced reciprocal translocations are one of the most common genetic causes of male infertility. The commonly accepted underlying pathophysiological mechanism is that they impair meiosis ...

Second cancers following pediatric Hodgkin's disease. Translocation (1;19)+ patients were more likely than t(1;19)- patients to be 10 years of age or greater (P < .001) or CD10+ CD19+ CD34- (P < .0001 ...

Background: Preimplantation genetic testing for aneuploidy (PGT-A) and structural rearrangement (PGT-SR) have been widely used within indications of previous miscarriages, repeated implantation ...

Translocation is a genetic abnormality in which part of a chromosome moves to another chromosome. Chromosomes are genetic structures within cells that hold genes. When translocation occurs, it causes ...

MONGOLISM is usually the result of trisomy of a small acrocentric chromosome in Group 21–22 in the Denver Classification. This is generally referred to as 21-trisomy. These patients have a somatic ...

Inside of each of your cells are thread-like structures made up of parts called chromosomes. These tightly wound threads are what people mean when they refer to your DNA. It’s a blueprint for cell ...